Boris Johnson's adviser has quit after a video showed her joking about a Christmas Party at Downing Street last year while London was under Tier 3 restrictions.

Newly released pictures chart Ghislaine Maxwell's relationship with disgraced billionaire Jeffrey Epstein, with images shown to court of the pair kissing and of Maxwell massaging Epstein.

Three shots of the Pfizer/BioNTech COVID-19 vaccine has been shown to generate a neutralising effect against the new Omicron variant in a laboratory test.

Boris Johnson has not ruled out the imposition of fresh coronavirus restrictions in England and a move to Plan B of the government's strategy for dealing with COVID-19 this winter.

Boris Johnson has apologised after footage emerged of senior Number 10 officials joking and laughing about a Downing Street Christmas party last year, but told MPs he has been "repeatedly assured" no such gathering took place.